It is a variant on Zhang Zhong-jing Si Ni San (Formula for Frigid Extremities) from the Treatise on Cold-induced Diseases (shang han lun). The latter formula was originally designed to treat the effects of exogenous pathogenic Cold as it penetrated the Interior, transformed into Heat and trapped the Yang Qi on the Interior, leading to cold extremities.
As with many of Zhang Zhong-jings formulas from the Shang Han Lun, this one was so ingeniously designed that its use has been expanded over subsequent centuries to include a broad range of disorders in this case, those due to Liver Qi constraint with the development of Blood stasis. In order to focus the formulas actions in this way, Zhang Jing-yue substituted mature Citrus fruit (zhi ke), for the immature fruit (zhi shi) and added Cyperus (xiang fu), Citrus peel (chen pi) and Ligusticum (chuan xiong).
Bupleurum falcatum (Bupleurum) root extract 20.25 mg
equiv. root dry 43.8 mg
Citrus aurantium (Bitter Orange) fruit extract 26.99 mg
equiv. fruit dry 58.43 mg
Corydalis turtschaninovii (Corydalis) rhizome extract 20.25 mg
equiv. rhizome dry 43.84 mg
Curcuma longa (Turmeric) root extract 20.25 mg
equiv. root dry 43.84 mg
Cyperus rotundus rhizome extract 26.99 mg
equiv. rhizome dry 58.43 mg
Glycyrrhiza uralensis (Licorice) root extract 11.24 mg
equiv. root dry 24.34 mg
Ligusticum wallichii rhizome extract 20.25 mg
equiv. rhizome dry 43.84 mg
Paeonia lactiflora (Peony) root extract 27.01 mg
equiv. root dry 58.46 mg
Caution for those on anti-coagulant medications (i.e. Heparin, warfarin or aspirin).
Caution for those on any type of sedative drug.
Contraindicated for patients taking interferon.
Contraindicated during pregnancy.
Talk to a TCM practitioner/health professional if you are unsure if this medicine is right for you.
Adults: 8 pills three times daily with warm water, half to one hour away from food, or as directed by your healthcare practitioner.
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