This work is the earliest surviving record that details the diagnosis and treatment of miscellaneous diseases of internal medicine, as well as some surgical diseases and gynaecological disorders, according to the Eight Principles.
The original formula has been enhanced with the addition of Albizia flower (he huan hua), and Polygala root (yuan zhi), which are commonly used in the treatment of mental- emotional unrest. The formula was classified under treatments for 'consumptive diseases' (xu lao), which is a class of severe deficiency syndromes in which the Qi, Blood, Yin or Yang of the Zang-fu organs has become 'consumed', i.e. severely depleted.
These are typically chronic lingering conditions that do not manifest with any one predominating symptom. However, the modified version is specifically directed towards insomnia and mental unrest occurring in cases with Liver Blood deficiency and the various secondary imbalances that have arisen as a result of it: deficiency Heat, Yang hyperactivity, Liver Qi constraint and Heart Blood deficiency and Liver Yin deficiency.
In this way, the formula may have a powerful tranquilising action that is brought about by nourishing the Blood and Yin as well as clearing deficiency Heat. It may therefore be suitable for patients with insomnia, primarily due to Liver deficiency. The key signs are irritability, impatience and a wiry pulse.
The synergistic actions of the herbs are as follows:
Ziziphus seed (suan zao ren), Albizia flower (he huan hua), Polygala root (yuan zhi): nourish the Liver and Heart, calm the Spirit
Wolfiporia cocos (fu ling): tonifies the Spleen (and Stomach) Qi, calms the Spirit.
Anemarrhena rhizome (zhi mu), Glycyrrhiza root (gan cao): clear deficiency Heat and soothe irritability, protect against the harsh and drying nature of Ligusticum (chuan xiong).
• Ligusticum rhizome (chuan xiong): regulates the Qi and Blood, soothes the Liver.
• Albizia flower (he huan hua): regulates the Qi and soothes the Liver, nourishes the Heart and calms the Spirit.
• Polygala root (yuan zhi): directs the actions of the formula to the Heart.
• Angelica root (dang gui), Paeonia root (bai shao): nourish the Heart and Liver Blood
Albizia julibrissin (Albizia/Mimosa) flower extract 17.33 mg
equiv. flower dry 37.43 mg
Anemarrhena asphodeloides (Anemarrhena) rhizome extract 23.1 mg
equiv. rhizome dry 49.9 mg
Angelica polymorpha (Dong Quai) root extract 23.1 mg
equiv. stem dry 49.9 mg
Glycyrrhiza uralensis (Licorice) root extract 9.63 mg
equiv. root dry 20.81 mg
Ligusticum wallichii rhizome extract 17.33 mg
equiv. rhizome dry 41.2 mg
Paeonia lactiflora (Peony) root extract 23.1 mg
equiv. root dry 49.9 mg
Polygala sibirica (Polygala sibirica) root extract 9.63 mg
equiv. root dry 20.81 mg
Wolfiporia cocos (Poria) fruiting body extract (hyphae) 23.1 mg
equiv. hyphae dry 49.9 mg
Ziziphus jujuba var. spinosa (Zizyphus) seed extract 28.7 mg
equiv. fruit dry 61.99 mg
Avoid caffeine containing beverages (i.e. coffee, tea, cola drinks, guarana), especially in the afternoon.
Caution in patients using sedative-hypnotic medications.
8 pills three times daily, half to one hour away from food.
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