Herbs of Gold Activated B Stress 60 Tablets

 Activated B Stress is a convenient blend of all the B complex

vitamins, including biotin, plus antioxidant vitamin C and proprietary

Holixer™ to address symptoms of stress in a single complex.

• Activated B Stress contains all four available activated B vitamins:

– Riboflavin-5-phosphate, the active form of vitamin B2

– Pyridoxal 5-phosphate (P5P), the active form of vitamin B6

– Methylfolate, the active form of folic acid

– Methylcobalamin, the active form of vitamin B12

• As both B vitamins and vitamin C are water-soluble and generally

not stored in the body, regular daily intake is required to support

general health. B vitamins work synergistically in the body, and

are, therefore, best taken together.

• Increased adherence to the typical Western diet (high

consumption of processed meet, red meat, butter, high-fat dairy

products, eggs and refined grains and sugars) is associated with

decreased vitamin and mineral intake, including most of the B

vitamins1

. This, combined with increased levels of stress in the

general population, highlights the key role vitamins can play in

supporting a healthy stress response.

Each tablet contains:

Ocimum tenuiflorum (Holy basil) herb top extract (HOLIXER™) 250mg

derived from dry herb.................................................................................................................................................... 5g

Thiamine hydrochloride.. ...................................................................................................................................25.42mg

 equiv. Thiamine (vitamin B1) 20mg

Riboflavin sodium phosphate................................................................................................................................20mg

 equiv. Riboflavin (vitamin B2) 14.64mg

Nicotinamide...............................................................................................................................................................20mg

Calcium pantothenate.............................................................................................................................................50mg

 equiv. Pantothenic acid (vitamin B5) 45.88mg

Pyridoxal 5-phosphate monohydrate.................................................................................................................20mg

 equiv. Pyridoxine (vitamin B6) 12.76mg

Levomefolate glucosamine (Quatrefolic®).....................................................................................632 micrograms

 equiv. Levomefolic acid (5-MTHF) 300 micrograms

Mecobalamin (co-methylcobalamin) (vitamin B12).................................................................. 300 micrograms

Biotin......................................................................................................................................................... 300 micrograms

Ascorbic acid (vitamin C)......................................................................................................................................250mg

DRUG INTERACTIONS

• Caution with cholestyramine and colestipol (hypolipidaemic

agents) - may decrease the absorption of vitamin B3 and folate.

Separate dose by at least 4-6 hours.

• Caution with phenobarbital and phenytoin (anticonvulsants) – high

doses of vitamin B6 or folate can decrease their efficacy. Monitor.

• Caution with L-Dopa - vitamin B6 increases the peripheral

metabolism of levodopa and may lower levodopa levels for

CNS penetration, resulting in reduced levodopa effects. The

effect of pyridoxine is prevented by administration of a dopadecarboxylase inhibitor (e.g. benserazide, carbidopa) with

levodopa, as is common clinical practice.

• Caution with antiepileptic and anticonvulsant medications – folic

acid may reduce serum levels of these medications. Patients should

take folate only under the supervision of a health professional.

• Caution with methotrexate (folic acid antagonist) - coadministration with folate may reduce the effects. Patients should

take folate only under the supervision of a health professional.

• Caution with tetracycline hydrochloride (antibiotic) - B vitamins

may reduce drug bioavailability. Separate dose by at least 2 hours.

• Several medications may deplete folate status, including

trimethoprim (antibiotic), pyrimethamine (antimalarial),

triamterene (blood pressure), sulfasalazine (for ulcerative colitis)

and oral contraceptives.

• Several medications can decrease the absorption of vitamin

B12 or increase the risk of deficiency, such as acid-suppressing

medications (proton-pump inhibitors e.g. omeprazole

and histamine2 (h2)-receptor antagonists), metformin

(hypoglycaemic), oral contraceptives, neomycin (antibiotic) and

colchicine (anti-gout).

• Caution with antacids - vitamin C increases the amount of

aluminium absorbed. Separate doses by 2 hours.

CAUTIONS

• B vitamins are stimulatory in nature. To avoid any sleep

interference, avoid taking before bed.

• Taking at night may result in more vivid dreams (vitamin B6).

• Use in caution if there is a history of renal impairment or renal

calculi (kidney stones) as vitamin C (ascorbic acid) may increase

the risk of recurrence of calcium oxalate calculi.

• Caution in iron overload conditions, such as haemochromatosis,

as vitamin C can increase iron absorption.

SIDE EFFECTS

 • Supplemental B vitamins may cause nausea or mild

gastrointestinal upset if taken on an empty stomach. Best taken

with food to reduce risk.

• Riboflavin can impart a bright yellow colour to urine. 

Adults and children over 12 years - Take 1 tablet daily, with food, or as directed by your health professional.

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